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Glucosylceramide synthase-IN-3 (compound BZ1) is a potent, brain-penetrant, and orally active glucosylceramide synthase (GCS) inhibitor with an IC50 of 16 nM for human GCS. It can be used for Gaucher's disease research.
Storage conditions for powder: -20°C for 3 years
Storage conditions for powder: 4°C for 2 years
Storage conditions in solvent: -80°C for 6 months
Storage conditions in solvent: -20°C for 1 month
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Cymoxanil (CAS No 57966-95-7) is a fungicide primarily used within agricultural research Originating from a class of cyanoacetamide oximes its mechanism of action involves the inhibition of fungal growth by disrupting the spore germination process and interfering with the normal function of fungal mitochondrial pathways Its in vitro activity is commonly observed within the nanomolar to low micromolar range demonstrating efficacy in various biological assays Cymoxanil is typically applied in studies involving plant tissue cultures greenhouse trials and field studies where it serves as a crucial component of integrated pest management systems Additionally it is often utilized in drug screening programs to evaluate antifungal potentials Experimental concentrations are typically determined based on the specific research design with consideration for factors such as pathogen type environmental conditions and target crop species
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